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Thursday 28 February 2013

In Theory; Under Stress, Insulin-Making Cells Revert to Nascent State.

Schaffer, Amanda. IN THEORY; Under Stress, Insulin-Making Cells Revert to Nascent State. The new-fangled York Times. The New York Times, 02 Oct. 2012. Web. 01 Oct. 2012. .

This article describes the recent advances in search regarding diabetes and insulin proceeds. Scientists erst thought that people with diabetes became resistant to insulin, which would in turn let their insulin-producing beta cells to overwork and die out. Now researchers are hypothesizing that the simplification of insulin in the body is actually due to a variegate in the beta cells form, not their death. They believe that the beta cells repay to a progenitor state in which they are ineffectual to produce insulin, and reversing this process could help cure diabetes. New research also shows that a protein called FOXO1, which disappears as beta cells stop producing insulin, is decisive to keeping the production of insulin in beta cells running. Researchers found that mice that were unresolved to stress and lacked the protein ended up developing signs of Type 2 diabetes. Some of their beta cells were found to have reverted to the progenitor state, a wish to the findings of the earlier study.

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These findings are important be hasten they show that physiological stresses cause an increase in the demand on beta cells for insulin, in turn causing the progression of diabetes. Currently, treatments for diabetes are pushing the production of insulin, which could actually be speeding up the transformation of beta cells to progenitor cells. We could use this information to try to change our methods of treating diabetes and bring on more efficient and successful drugs.
I believe that the causation could have done a better job rationalizeing the modulation between beta cells and progenitor cells. She also doesnt explain the idea about stress to well; it seems more like an assumption of her own than an idea based on concrete evidence. Other than this, I think she did well summarizing the results of the experiments and...If you want to baffle a full essay, order it on our website: Ordercustompaper.com



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